PRAXBIND (idarucizumab) is a sterile, preservative-free,ncolorless to slightly yellow, clear to slightly opalescent solutionnfor intravenous administration.Using recombinant expressionntechnology, idarucizumab is produced in a well characterized recombinantn(mammalian) CHO cell line and is purified using standard technology.nIdarucizumab is composed of a light chain of 219 amino acids and anheavy chain fragment of 225 amino acids, covalently linked togethernby one disulfide bond between cysteine 225 of the heavy chain fragmentnand cysteine 219 of the light chain, and has an estimated molecularnmass of approximately 47,766 Daltons. ![]() Idarucizumab is a humanized monoclonal antibodynfragment (Fab) derived from an IgG1 isotype molecule, whose targetnis the direct thrombin inhibitor dabigatran.
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